Find patient medical information for Pepcid Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids. Prilosec (omeprazole) gives you long-lasting heartburn relief but has some risks if used long term. Time to complete relief of daytime and nighttime pain was statistically significantly shorter for patients receiving Pepcid than for patients receiving placebo; however, in neither study was there a statistically significant difference in the proportion of patients whose pain was relieved by the end of the study (week 8). Prilosec and Diarrhea -- How Common Is It? Before medicines are approved, they must go through several clinical studies in which thousands of people are given a particular medicine and are then compared to a group of people not given the medicine. Are you giving Pepcid a/c (famotidine), Zantac (ranitidine) or Prilosec (omeprazole) to your cat? It turns out, you may be contributing to your cat's illness. There is no known interaction between Pepcid Complete and Tylenol in our records. However, an interaction may still exist. INDICATIONS. PEPCID is indicated in: Short-term treatment of active duodenal ulcer. Most adult patients heal within 4 weeks; there is rarely reason to use PEPCID at full dosage for longer than 6 to 8 weeks. Several studies show that medications like Prilosec provide better relief and overall healing from acidic damage than H2-blocking medications like Pepcid and Zantac. Prilosec (Omeprazole) is used to treat symptoms of gastroesophageal reflux disease (GERD), erosive esophagitis and Zollinger-Ellison syndrome. Easy-to-read patient leaflet for Pepcid AC Chewable Tablets. Includes indications, proper use, special instructions, precautions, and possible side effects.